At least three people have been taken to hospital following a crash in the eastbound lanes of Highway 401 two kilometres east of Marysville Road.
Initial and unconfirmed reports from the scene indicate a black Suburban SUV hit a tree on the south side of the road with five people inside.
Also at this hour, emergency crews are at the scene of a two-vehicle collision on Wallbridge-Loyalist Road.
First reports indicate the doors are jammed on one vehicle and the crews may have to extricate at least one person.
Police are reminding motorists that the roadways are extremely slippery, plan ahead and drive to the conditions.